how soon will items be disappeared in minecraft if they are not been picked up by players

In Minecraft, items have a certain lifespan after being dropped or spawned in the world. If an item is not picked up by a player or collected by an entity, it will eventually "despawn" or disappear. The conditions under which items despawn are as follows:

1. Distance from Player: Items will only despawn if they are more than a certain distance from any player. This range has changed over versions of Minecraft, but as of the Java Edition 1.17, the despawn distance is approximately 80 blocks around players and observers.

2. Time Limit: Items will despawn after a certain amount of time. In the Java Edition, this time limit is approximately 5 minutes.

3. Block Entity Limit: The game area can only hold so many block entities (e.g., chests, furnaces, note blocks, etc.). When this limit is reached, items may despawn if there are too many other block entities nearby.

4. Entity Limit: There's also an overall limit to the number of entities in the world. If this limit is exceeded, items may despawn.

5. Specific Game Rules: Some games with custom settings might adjust the despawning mechanics, potentially making items despawn faster or slower.

It's worth noting that items in containers, such as chests or barrels, do not despawn. When stored in such containers, they persist indefinitely unless the container is destroyed.

Keep in mind that these factors could vary slightly depending on the specific version of Minecraft you're playing (Java Edition, Bedrock Edition, etc.) and any modifications or plugins that may alter the game's mechanics.